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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PKN3
All Species:
15.45
Human Site:
T480
Identified Species:
24.29
UniProt:
Q6P5Z2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P5Z2
NP_037487.2
889
99421
T480
P
P
K
G
C
P
R
T
P
T
T
L
R
E
A
Chimpanzee
Pan troglodytes
XP_001159776
886
99121
T477
P
P
K
G
C
P
R
T
P
T
T
L
R
E
A
Rhesus Macaque
Macaca mulatta
XP_001110500
1011
111864
T593
P
P
K
G
C
P
R
T
P
T
T
S
R
E
A
Dog
Lupus familis
XP_548434
951
104664
T542
P
P
K
A
C
P
Q
T
P
A
T
P
R
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K045
878
97863
G469
N
T
A
S
P
P
K
G
R
P
S
T
A
V
C
Rat
Rattus norvegicus
O08874
985
112050
T544
P
Q
T
P
V
P
A
T
V
P
V
V
D
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506565
993
109767
R578
S
T
L
S
P
P
S
R
T
P
A
H
A
P
A
Chicken
Gallus gallus
XP_422357
1013
114806
P616
S
L
G
E
I
C
E
P
S
S
E
M
K
A
P
Frog
Xenopus laevis
Q7ZX15
486
56292
G148
M
D
V
A
M
S
K
G
H
P
K
V
T
M
N
Zebra Danio
Brachydanio rerio
XP_697542
940
106140
P532
P
P
L
P
G
S
E
P
L
S
P
P
S
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
G296
A
T
G
E
T
R
P
G
K
C
S
L
L
D
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34885
707
80133
D356
L
Q
Q
I
S
E
D
D
S
G
T
T
S
S
R
Sea Urchin
Strong. purpuratus
XP_787090
799
90414
R369
P
P
T
A
I
R
P
R
P
P
I
Q
R
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
T599
Q
P
R
K
H
D
K
T
P
S
P
Q
K
V
G
Red Bread Mold
Neurospora crassa
P87253
1142
127954
K726
Y
G
S
P
Q
Q
R
K
Y
N
P
A
D
Y
A
Conservation
Percent
Protein Identity:
100
97.7
81.5
84.2
N.A.
83.2
49.9
N.A.
64.2
48.9
26.2
52.2
N.A.
28
N.A.
29.1
41.5
Protein Similarity:
100
97.8
82.9
87.6
N.A.
88.4
63.6
N.A.
72.9
63
36.6
67.6
N.A.
41.5
N.A.
43.9
58.2
P-Site Identity:
100
100
93.3
66.6
N.A.
6.6
20
N.A.
13.3
0
0
13.3
N.A.
6.6
N.A.
6.6
26.6
P-Site Similarity:
100
100
93.3
73.3
N.A.
20
26.6
N.A.
13.3
20
13.3
26.6
N.A.
20
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.2
27.1
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41.7
43.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
7
20
0
0
7
0
0
7
7
7
14
14
40
% A
% Cys:
0
0
0
0
27
7
0
0
0
7
0
0
0
0
7
% C
% Asp:
0
7
0
0
0
7
7
7
0
0
0
0
14
7
0
% D
% Glu:
0
0
0
14
0
7
14
0
0
0
7
0
0
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% F
% Gly:
0
7
14
20
7
0
0
20
0
7
0
0
0
7
7
% G
% His:
0
0
0
0
7
0
0
0
7
0
0
7
0
0
0
% H
% Ile:
0
0
0
7
14
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
27
7
0
0
20
7
7
0
7
0
14
0
0
% K
% Leu:
7
7
14
0
0
0
0
0
7
0
0
20
7
7
0
% L
% Met:
7
0
0
0
7
0
0
0
0
0
0
7
0
7
0
% M
% Asn:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% N
% Pro:
47
47
0
20
14
47
14
14
40
34
20
14
0
7
7
% P
% Gln:
7
14
7
0
7
7
7
0
0
0
0
14
0
0
0
% Q
% Arg:
0
0
7
0
0
14
27
14
7
0
0
0
34
0
14
% R
% Ser:
14
0
7
14
7
14
7
0
14
20
14
7
14
7
14
% S
% Thr:
0
20
14
0
7
0
0
40
7
20
34
14
7
0
0
% T
% Val:
0
0
7
0
7
0
0
0
7
0
7
14
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
7
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _